The Gut-Brain Connection: A Holistic Approach to Mental Health

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Dr. Pinkston is working hard to create a new vision for health and wellness by re-entering the radio waves coming in April! Dr Pinkston is a graduate of the University of Texas Health Science Center, San Antonio and of the Christus Santa Rosa family practice residency program. Graduating in 1997 and starting her clinical solo practice in 2000, Dr. Pinkston provided South Texas with the best general care in family practice until 2007 when she developed Rheumatoid Arthritis. Through diet, exercise, hormones, mind and body techniques she has regained her health and wants to help others discover their own path to wellness. She will have the local radio show with a national platform on Sirius XM and will have a podcast, blog and YouTube channel! Stay tuned as developments are happening EVERYDAY!

  

Bio

Dr. Marianne Pinkston is a graduate of the University of Texas Health Science Center, San Antonio and of the CHRISTUS Santa Rosa Family Practice Residency Program. Graduating in 1997 and starting her clinical solo practice in 2000, Dr. Pinkston provided South Texas with the best general care in family practice until 2007 when she developed Rheumatoid arthritis. Rheumatoid arthritis is a severe disabling inflammatory arthritis condition of all the joints that includes severe debilitating fatigue and other issues. Dr. Pinkston then began her journey into integrative and functional medicine where she has earned tens of thousands of hours in training and degrees in stem cell and peptide certification as well as anti-aging and regenerative medicine studies and in integrative medicine studies. Dr. Pinkston is a specialist of weight loss having her self gained up to 300 pounds and developed diabetes and high blood pressure, dr. Pinkston lost 162 pounds in a year and two months regaining her precious health. Dr. Pinkston also provides the best in hormone replacement therapy for men and women and treats autoimmune conditions as well as thyroid and diabetic and other inflammatory conditions. Dr. Pinkston is not limited to any certain disease or treatment style. Dr. Pinkston entered into the mass media scene in 2016 with KTSA 550 and the Dr Pinkston’s Radio Show and now has joined with KLUP-930 The Answer in San Antonio Texas where she will present many contemporary and integrative health topics as well as inspirational and guided life improvement topics and motivational speaking. Dr. Pinkston is a board of director and speaker for Global Pain Association having suffered chronic pain for 14 years and is the president of Pinkston Medical and Wellness Clinic under Total Care Physical Therapy And Rehab. She continues as a solo practitioner in San Antonio Texas treating all ages and men and women for all conditions. Dr. Pinkston is the premier specialist of Hormone Replacement Therapy and of wellness and anti-aging and is medical director of the Dolce Beauty and Laser medical spa. Dr. Pinkston has over 10,000 hours of teaching for medical students and Nurse Practitioner and physician assistants. She is extremely active in the community and in many philanthropic areas and continues in private practice. Dr. Pinkston is sponsored by PD labs in Austin Texas and join forces with pharmacist Ray Solano on Healthy Choices channel on Sirius XM and has developed a blog a podcast and a YouTube channel where you can find Dr. Pinkston at any time. Dr. Pinkston’s mission is to give patients and everyone everywhere the better life.

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Saturday, September 27, 2025

In this episode of The Better Life, Dr. Marianne Pinkston and guest Ray Solano, owner of PD Labs, a compounding pharmacy, explore the intricate link between gut health and neurological well-being. They discuss how an integrative approach, combining functional medicine principles with modern therapeutics, can address the root causes of mental health conditions like anxiety, depression, and ADHD. The conversation covers the impact of diet, genetics, and lifestyle on mental health, and introduces natural and compounded solutions like L-theanine, oxytocin, and BH4.

Chapters

    0:00 - 4:14: Introduction and the Problem with Conventional Solutions. Dr. Pinkston introduces Ray Solano and the topic of neurological problems. They discuss the rising rates of conditions like depression and ADD and argue that conventional medicine often only treats symptoms with pharmaceuticals, ignoring the root causes.

    4:14 - 8:40: The Gut-Brain Connection and Inflammatory Foods. Ray and Dr. Pinkston explain the direct link between gut health and brain function, highlighting how neurotransmitters are made in the GI tract. They emphasize that inflammatory foods like gluten, processed items, and alcohol can significantly impact mental health.

    8:40 - 13:28: The Role of Genetics and Foundational Treatments. The discussion shifts to the role of genetic predispositions (SNPs) and how lifestyle and diet can either turn these genes on or off. They introduce the importance of a holistic approach, viewing health as a puzzle with multiple pieces, including nutrition, exercise, sleep, and gut health.

    13:28 - 19:38: Nutraceuticals and Hormonal Support. Dr. Pinkston and Ray detail natural, accessible remedies. Ray highlights L-theanine for its calming effects and introduces oxytocin, explaining its role in social bonding and mood elevation. They discuss its use as a compounded treatment for conditions like OCD and autism.

    19:38 - 25:22: The Power of Compounded Pharmaceuticals. The focus returns to specific, targeted solutions. Ray explains BH4 (tetrahydrobiopterin), a pharmaceutical used to treat a specific genetic deficiency that impacts serotonin and dopamine production. They also discuss the compounding of natural thyroid medication and the importance of personalized medicine.

    25:22 - 30:40: Progesterone and Metabolic Dysfunction. The conversation broadens to include hormonal balance, with Dr. Pinkston highlighting progesterone's role in sleep and anxiety. They also discuss metabolic dysfunction, the prevalence of belly fat, and its link to hormonal disruption and chronic disease.

    30:40 - 34:25: Addressing ADD and Brain Inflammation. Dr. Pinkston and Ray focus on ADD and the importance of removing inflammatory foods from the diet. Ray introduces Synapsin, a compounded nasal spray containing RG3-Ginseng, as an effective tool for reducing brain inflammation associated with ADD and other neurological issues.

    34:25 - 39:05: Conclusion and Final Thoughts. Dr. Pinkston and Ray encourage listeners to seek professional support for their health issues. They emphasize the value of telehealth and the growing field of longevity medicine, which aims to fix underlying problems rather than just treating symptoms. They conclude by providing contact information for their respective websites and podcasts.

Visit my website: https://www.drpbetterlife.com/

Connect with me on social media:
https://www.facebook.com/pinkston4life
https://instagram.com/drmariannepinkston
https://www.linkedin.com/in/marianne-pinkston-md-857ba069
https://twitter.com/pinkston4life
https://www.tiktok.com/@drmariannepinkston

 

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